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Cellulose-Based Stationary Phase Immobilized via Click Chemistry

Glycoconjugate synthesis

Cellulose-Based Stationary Phase Immobilized <em>via</em> Click Chemistry
October 10, 2025
Cellulose-Based Stationary Phase Immobilized via Click Chemistry

On April 07, 2025, a groundbreaking study by Lehrhofer et al. published in Cellulose demonstrated the strategic application of Cu(I)-catalyzed azide-alkyne click chemistry to covalently immobilize a cellulose per(phenyl carbamate) chiral selector onto silica gel, overcoming critical limitations of traditional coated stationary phases. This research addresses the solvent-induced bleeding issue in HPLC enantiomer separation by […]

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