Experience the Exceptional Mesenchymal Stem Cell (MSC)-based Drug Delivery Solutions

MSCs are pluripotent stem cells with the ability of self-renewal and multidirectional differentiation. They are widely used in drug delivery, tissue engineering, and regenerative medicine because of their immunomodulatory, anti-inflammatory, and tissue repair functions. CD BioGlyco has decades of research experience in the field of GlycoCLICK™-based Drug Delivery. We offer MSC-based drug delivery solutions that are specifically tailored to the unique research requirements of clients. We utilize MSCs as carriers of drugs for targeted drug delivery and release by altering the surface properties and functions of MSCs. Our strategies include but are not limited to the following.

• We encapsulate the cell membrane of MSCs on the surface of nanoparticles to form cell membrane-encapsulated nanoparticles. This method takes advantage of the tumor chemotaxis of MSC to deliver anti-tumor drugs into the tumor tissue to enhance targeting. The targeting and drug-release ability of nanoparticles can be enhanced by cell membrane-coated nanoparticles.
• Another strategy is that we co-culture MSCs with drug or gene vectors so that they take up and release the drug or gene. This takes advantage of the high migration and targeting ability of MSCs to deliver drugs or genes to tissues near inflammation or injury. By co-culturing MSCs with drug or gene vectors, the MSCs have the function of drug delivery or gene delivery.
• We transform MSCs through an advanced recombinant gene process. We use a specialized gene transfer system to infiltrate the cells and make them express specific genes. This process aims to alter the function of MSCs. More specifically, this functional alteration enhances the role of MSCs in drug delivery. The altered MSCs can target specific sites in the body where drugs are needed, which helps to increase the efficiency of drug delivery and improve the precision of drug delivery.

Publication Data

Applications

• MSCs are used as model cells for drug screening to help evaluate the toxicity and efficacy of drugs and accelerate the process of new drug development.
• The ability of MSCs to produce a factor capable of suppressing immune cells has led to the use of MSCs in the study of immune-related diseases.
• MSCs are capable of differentiating into many different types of cells, so MSCs are used in the research of repairing and regenerating damaged tissues.

Advantages

• MSCs can be delivered through a variety of routes, including direct injection, targeted delivery, implantation of stents, etc., so we choose the most suitable delivery method for your specific needs.
• MSCs exhibit a lower immunogenicity, resulting in reduced immune rejection and improved delivery effectiveness.
• MSCs have the potential for multidirectional differentiation, allowing them to serve both as drug delivery vehicles and tissue repair agents, thereby offering expanded possibilities for your research.

CD BioGlyco provides clients with professional and complete MSC-based drug delivery services. We maintain flexibility in our projects through adaptable project management and customized solutions to provide you with a highly satisfactory service experience. If you would like more information about our services, please feel free to contact us.

• β-Cyclodextrin (CD)-based Drug Delivery Service
• Agarose-based Drug Delivery Service
• Nanometabolic Precursors (Nano-MP)-based Drug Delivery Service
• Gel Stent-based Drug Delivery Service
• Polymer-based Drug Delivery Service
• Silica-based Nanoparticle Drug Delivery Service
• Chitosan-based Nanoparticle Drug Delivery Service
• Bioreactor-based Drug Delivery Service
• SPAAC-based Drug Delivery Service
• CuAAC-based Drug Delivery Service
• Diels-Alder Reaction-based Drug Delivery Service
• Staudinger Reaction-based Drug Delivery Service