DBCO PEG reagent, DBCO-PEG6-DBCO, Purity 95%

Synonym: DBCO-PEG6-DBCO; BP-25735

PubChem CID: 156598865

Size

25 mg; 50 mg; 100 mg; 250 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

DBCO-PEG6-DBCO is a specialized click chemistry linker characterized by two terminal DBCO groups connected by a hydrophilic PEG spacer arm. The DBCO groups facilitate rapid and efficient reactions with azide-bearing compounds or biomolecules, forming stable triazole linkages without the need for a copper catalyst. Meanwhile, the PEG spacer arm not only enhances water solubility but also improves membrane permeability, ensuring versatile and effective bioconjugation applications.

Molecular Weight

899.1

Molecular Formula

C₅₂H₅₈N₄O₁₀

Functional Group 1

DBCO

Functional Group 2

None

Functional Group 3

None

Reactive Group 1

Azide

Form

Solid

Purity

95%

Identity

Confirmed by NMR.

Applications

DBCO-PEG6-DBCO is invaluable for bioconjugation studies and chemical biology applications, offering precise and selective labeling of biomolecules. Its dual DBCO functionality enables the simultaneous modification of two different targets or the cross-linking of biomolecules for the formation of macromolecular complexes. The absence of copper in the click chemistry reaction ensures compatibility with sensitive biological systems and avoids potential cytotoxicity.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.