Amine/Azide PEG reagent, Aminooxy-PEG4-azide, Purity 98%

Synonym: 2100306-61-2; Aminooxy-PEG4-azide; O-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethyl]hydroxylamine

CAS Number: 2100306-61-2
PubChem CID: 126480410

Size

100 mg; 250 mg; 500 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Aminooxy-PEG4-azide is a heterobifunctional crosslinker that features both an aminooxy group and an azide group. The aminooxy moiety can be utilized in bioconjugation, reacting with aldehydes to form oxime bonds. When a reductant is present, it will create hydroxylamine linkages instead. The azide group can engage in reactions with alkynes, BCN, or DBCO through click chemistry, resulting in stable triazole linkages.

Molecular Weight

278.3

Molecular Formula

C₁₀H₂₂N₄O₅

Functional Group 1

Amine

Functional Group 2

Azide

Functional Group 3

None

Reactive Group 1

Acid

Reactive Group 2

Alkyne

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

This compound finds application in click chemistry and bioconjugation reactions. The aminooxy group can react with aldehydes and ketones to form stable oxime linkages. The PEG4 moiety enhances solubility and biocompatibility. It is used for the modification of biomolecules such as proteins and nucleic acids, as well as in the synthesis of drug delivery systems and nanomaterials for targeted therapy.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.