Amine/DBCO PEG reagent, DBCO-PEG2-amine, Purity 98%

Synonym: 2250216-96-5; DBCO-PEG2-amine; DBCO-PEG2-amine TFA salt; DBCO-C4-PEG2-amine; AKOS040743193

CAS Number: 2250216-96-5
PubChem CID: 134827742

Size

50 mg; 100 mg; 250 mg; 500 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

DBCO-PEG2-amine is a versatile PEG linker featuring both DBCO and amine functional groups. The DBCO moiety is widely employed in copper-free Click Chemistry reactions, facilitating bioconjugation and chemical synthesis processes. Concurrently, the amine group offers reactivity with various functional groups such as carboxylic acids, activated NHS esters, and carbonyls (ketone, aldehyde). The inclusion of a hydrophilic PEG spacer enhances the compound's water solubility, making it suitable for aqueous-based applications.

Molecular Weight

435.5

Molecular Formula

C₂₅H₂₉N₃O₄

Functional Group 1

Amine

Functional Group 2

DBCO

Functional Group 3

None

Reactive Group 1

Carboxylic acid

Reactive Group 2

Carbonyls

Reactive Group 3

NHS

Form

Liquid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

DBCO-PEG2-amine can be used in a broad spectrum of research and development endeavors, particularly in the fields of bioconjugation, drug delivery, and materials science. Its compatibility with copper-free Click Chemistry enables efficient coupling reactions without the need for toxic copper catalysts, making it ideal for labeling biomolecules and constructing complex molecular architectures.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.