Bromoacetamidoacetamido PEG reagent, Bromoacetamido-PEG3-acid, Purity 98%

Synonym: 1807534-79-7; Bromoacetamido-PEG3-Acid; Bromoacetamido-PEG3-C2-acid; 1-Bromo-2-oxo-6,9,12-trioxa-3-azapentadecan-15-oic acid; Bromoacetamido-PEG3-CH₂CH₂COOH; 3-[2-[2-[2-[(2-Bromoacetyl)amino]ethoxy]ethoxy]ethoxy]propanoic acid

CAS Number: 1807534-79-7
PubChem CID: 91809468

Size

100 mg; 250 mg; 500 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Bromoacetamido-PEG3-acid is a PEG linker featuring a bromide group and a terminal carboxylic acid. Its hydrophilic PEG spacer enhances solubility in aqueous media. The bromide (Br) serves as an effective leaving group for nucleophilic substitution reactions. The terminal carboxylic acid moiety facilitates the formation of stable amide bonds with primary amine groups in the presence of activators such as EDC or HATU.

Molecular Weight

342.2

Molecular Formula

C₁₁H₂₀BrNO₆

Functional Group 1

Bromoacetamidoacetamido

Functional Group 2

None

Functional Group 3

None

Reactive Group 1

Amine

Form

Liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

Bromoacetamido-PEG3-acid finds application in bioconjugation and chemical modification processes. Researchers utilize its terminal carboxylic acid functionality to efficiently conjugate molecules containing primary amine groups, including proteins, peptides, and oligonucleotides. Its hydrophilic PEG spacer aids in maintaining solubility and biocompatibility, making it suitable for various biomedical and pharmaceutical applications.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.