DBCO/STP PEG reagent, DBCO STP ester, Purity 95%

Synonym: 2268816-75-5; DBCO-STP ester

CAS Number: 2268816-75-5
PubChem CID: 164577358

Size

10 mg; 25 mg; 50 mg; 100 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

DBCO STP ester is a versatile water-soluble reagent featuring a terminal DBCO group and a STP ester group. This compound is specifically designed for the modification of peptides, antibodies, proteins, and other molecules containing amino groups. The STP esters offer a superior alternative to conventional N-hydroxysuccinimide (NHS) esters for coupling reactions in aqueous environments. Meanwhile, the DBCO group is widely recognized for its utility in copper-free Click Chemistry reactions, owing to its strain-promoted high energy.

Molecular Weight

546.5

Molecular Formula

C₂₆H₁₆F₄NO₆S

Functional Group 1

DBCO

Functional Group 2

STP

Functional Group 3

None

Reactive Group 1

NHS

Form

Solid

Purity

95%

Solubility

Water, DCM, DMF, DMSO

Identity

Confirmed by NMR.

Applications

DBCO STP ester can be used as a valuable tool in bioconjugation and chemical biology studies, facilitating the site-specific labeling and functionalization of biomolecules. Its compatibility with aqueous environments makes it particularly suitable for applications involving peptides, proteins, and antibodies, where maintaining their native conformation and activity is crucial. The STP ester functionality enables efficient coupling reactions under mild conditions, ensuring minimal perturbation to delicate biological systems.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.