DBCO PEG reagent, DBCO-PEG5-TFP ester, Purity 95%

Synonym: DBCO-PEG5-TFP Ester

PubChem CID: 164577361

Size

10 mg; 25 mg; 100 mg; 500 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

DBCO-PEG5-TFP ester is a versatile labeling reagent designed for the modification of proteins, antibodies, and other amine-containing biopolymers. With its amine-reactive TFP ester group, this reagent enables efficient and site-specific conjugation to primary amines on biomolecules. The incorporation of a hydrophilic polyethylene glycol (PEG) spacer arm ensures a long and flexible connection between the reactive group and the biomolecule, reducing steric hindrance and enhancing accessibility for ligation with complementary azide-containing molecules.

Molecular Weight

744.7

Molecular Formula

C₃₈H₄₀F₄N₂O₉

Functional Group 1

DBCO

Functional Group 2

None

Functional Group 3

None

Form

Reported

Purity

95%

Solubility

DMF, DMSO, DCM, THF, Chloroform

Identity

Confirmed by NMR.

Applications

DBCO-PEG5-TFP ester can be used in bioconjugation and biomolecule labeling studies, particularly in the development of bioconjugates for various biomedical and research purposes. By reacting selectively with primary amines, DBCO-PEG5-TFP ester facilitates the precise attachment of fluorophores, probes, or other functional moieties to target proteins or antibodies. The hydrophilic PEG spacer arm enhances solubility and flexibility, allowing for efficient conjugation without compromising the biological activity of the biomolecule.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.