DBCO/Hydroxy PEG reagent, Hydroxy-PEG7-DBCO, Purity 98%

Synonym: Hydroxy-PEG7-DBCO; BP-23991

PubChem CID: 155288699

Size

50 mg; 100 mg; 250 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Hydroxy-PEG7-DBCO is a functional PEG linker featuring a DBCO moiety and a terminal primary hydroxyl group. The hydroxyl group offers versatility by allowing reactions with various functional groups, while the hydrophilic PEG spacer arm enhances solubility of labeled molecules. The DBCO moiety facilitates copper-free Click Chemistry reactions, enabling efficient and bioorthogonal conjugation.

Molecular Weight

656.8

Molecular Formula

C₃₅H₄₈N₂O₁₀

Functional Group 1

DBCO

Functional Group 2

Hydroxy

Functional Group 3

None

Form

Liquid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Hydroxy-PEG7-DBCO is valuable in bioconjugation applications, particularly in the synthesis of labeled biomolecules for biomedical research and drug delivery. The primary hydroxyl group allows for flexible functionalization, enabling conjugation with diverse molecules or surfaces. Meanwhile, the DBCO moiety's compatibility with azides permits selective and efficient bioconjugation reactions under mild conditions. Its hydrophilic PEG spacer arm further enhances solubility, making it suitable for aqueous environments.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.