Cat. No.: X24-03-YW0307
DBCO/Hydroxy PEG reagent, Hydroxy-PEG7-DBCO, Purity 98%
Synonym: Hydroxy-PEG7-DBCO; BP-23991
Size
50 mg; 100 mg; 250 mg
Properties
Description
Hydroxy-PEG7-DBCO is a functional PEG linker featuring a DBCO moiety and a terminal primary hydroxyl group. The hydroxyl group offers versatility by allowing reactions with various functional groups, while the hydrophilic PEG spacer arm enhances solubility of labeled molecules. The DBCO moiety facilitates copper-free Click Chemistry reactions, enabling efficient and bioorthogonal conjugation.
Molecular Formula
C35H48N2O10
Functional Group 2
Hydroxy
Solubility
DMSO, DCM, DMF
Identity
Confirmed by NMR.
Applications
Hydroxy-PEG7-DBCO is valuable in bioconjugation applications, particularly in the synthesis of labeled biomolecules for biomedical research and drug delivery. The primary hydroxyl group allows for flexible functionalization, enabling conjugation with diverse molecules or surfaces. Meanwhile, the DBCO moiety's compatibility with azides permits selective and efficient bioconjugation reactions under mild conditions. Its hydrophilic PEG spacer arm further enhances solubility, making it suitable for aqueous environments.
For Research Use Only. Not For
Clinical Use.