Description
Bromo-PEG1-CH2CO2tBu is a PEG linker with a bromide group and a t-butyl protected carboxyl group. Its hydrophilic PEG spacer enhances solubility in aqueous media. The bromide (Br) is highly effective as a leaving group in nucleophilic substitution reactions. The t-butyl protected carboxyl group can be selectively deprotected under acidic conditions.
Applications
Bromo-PEG1-CH2CO2tBu can be used in bioconjugation and chemical synthesis applications. Its compatibility with aqueous environments makes it suitable for various conjugation reactions in biological settings. This linker is commonly employed in the modification of biomolecules, surface functionalization, and the synthesis of bioactive compounds and materials.