Azide/Biotin PEG reagent, Dde biotin azide plus, Purity 95%

Synonym: BP-28104

PubChem CID: 164577344

Size

1 mg; 5 mg; 25 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Dde biotin azide plus is a PEG compound featuring terminal biotin and azide functional groups, alongside a hydrazine-cleavable Dde moiety. This design incorporates a copper-chelating system to facilitate robust, active copper complexes, serving as both reactant and catalyst in CuAAC reactions. The Dde moiety can be selectively removed under mild conditions (2% aqueous hydrazine), liberating the biotin tag and any avidin conjugate attached to it.

Molecular Weight

834.1

Molecular Formula

C₃₈H₆₃N₁₁O₈S

Functional Group 1

Azide

Functional Group 2

Biotin

Functional Group 3

None

Form

Reported

Purity

95%

Identity

Confirmed by NMR.

Applications

Dde biotin azide plus can be used in bioconjugation strategies, particularly those involving the selective labeling of biomolecules via- click chemistry. The presence of biotin enables specific binding to avidin or streptavidin-based systems, facilitating protein purification, detection, or immobilization. Furthermore, the inclusion of the Dde moiety offers a controlled release mechanism for the biotin tag under mild conditions, enhancing the flexibility and precision of bioconjugation protocols.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.