Amine PEG reagent, Amino-PEG8-t-butyl ester, Purity 98%

Synonym: 756526-06-4; Amino-PEG8-t-butyl ester; Amino-PEG8-Boc; H₂N-PEG8-CH₂CH₂COOtBu; Amino-PEG8-COOtBu

CAS Number: 756526-06-4
PubChem CID: 53433575

Size

250 mg; 500 mg; 1 g; 5 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Amino-PEG8-t-butyl ester is a PEG linker featuring a monodisperse structure and comprising an amino group with a t-butyl protected carboxyl group. The presence of the t-butyl protected carboxyl group allows for controlled reactivity, which can be activated under specific conditions. Additionally, the amino group exhibits reactivity with various functional groups, including carboxylic acids, activated NHS esters, and carbonyls, providing versatility in bioconjugation and chemical modification applications.

Molecular Weight

497.6

Molecular Formula

C₂₃H₄₇NO₁₀

Functional Group 1

Amine

Functional Group 2

None

Functional Group 3

None

Reactive Group 1

Carboxylic acid

Reactive Group 2

Carbonyls

Reactive Group 3

NHS

Form

Liquid

Purity

98%

Solubility

Water, DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Amino-PEG8-t-butyl ester finds widespread application in bioconjugation, surface modification, and drug delivery systems. Its controlled reactivity enables precise functionalization of biomolecules and surfaces under mild conditions, making it ideal for conjugating targeting ligands, drugs, or imaging agents to biomolecules or nanoparticles.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.