Biotin/NHS PEG reagent, Biotin-PEG12-NHS ester, Purity 98%

Synonym: 365441-71-0; Biotin-PEG12-NHS ester; EZ-Link NHS-PEG12-biotin; Biotin-PEG24-NHS

CAS Number: 365441-71-0
PubChem CID: 58481068

Size

100 mg; 250 mg; 500 mg; 1 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Biotin-PEG12-NHS ester is a water-soluble biotinylation reagent with amine-reactive NHS ester functionality. This compound is specifically designed for conjugation with lysine residues or other N-terminal amine groups in biomolecules.

Molecular Weight

941.1

Molecular Formula

C₄₁H₇₂N₄O₁₈S

Functional Group 1

Biotin

Functional Group 2

NHS

Functional Group 3

None

Reactive Group 1

Amine

Form

Solid (low melting point)

Purity

98%

Identity

Confirmed by NMR.

Applications

Biotin-PEG12-NHS ester is ideal for labeling proteins, peptides, antibodies, and other amine-containing biomolecules. The NHS ester moiety enables selective coupling reactions with primary amines under mild conditions (pH 7-9), resulting in stable amide bonds. The hydrophilic PEG12 spacer enhances solubility in aqueous environments, facilitating efficient conjugation and minimizing nonspecific binding.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.