Precision and Quality Assured Agarose-based Drug Delivery at Your Fingertips

The role of agarose in drug delivery systems is to act as a carrier in which drugs are encapsulated and delivered inside the human body utilizing injection or oral administration. This technique has the advantages of controlled release, high efficiency, low toxicity, and biocompatibility and can be utilized in fields such as medicine, chemical, and food industries. CD BioGlyco has been at the forefront of the pharmaceutical industry for decades, offering our esteemed clients a highly specialized and innovative GlycoCLICK™-based Drug Delivery Service. The materials in our service include but are not limited to β-Cyclodextrin (CD), Agarose, and Nanometabolic Precursors (Nano-MP). One of our flagship services is our agarose-based drug delivery service, which has garnered widespread recognition for its exceptional efficacy and reliability.

• First, we add agarose powder to a buffer solution and dissolve it by heating and stirring. Then, compounds with click-responsive functional groups (e.g., alkynyl or azide groups) are added to the agarose solution, which undergoes a click reaction with agarose to form an agarose gel containing click-responsive functional groups.
• Secondly, we modify the drug to be delivered with a compound that has an affinity for the click-reactive functional group (e.g., a ligand with an alkyne or azide group). The drug is linked to the click-reactive functional group by a click reaction to form the drug-modified compound. We then add the drug-modified compound to the agarose gel containing the click-reactive functional group and mix it thoroughly. Through the click reaction, the drug-modified compound is linked to the agarose gel to realize the encapsulation of the drug.
• Finally, the drug-modified agarose mixture is carefully poured into the mold to achieve the desired shape and undergoes a curing process. The drug will be released in a controlled manner in an appropriate buffer solution.

Fig.1 Process of agarose-based drug delivery service. (CD BioGlyco)

Publication Data

Applications

• Agarose has good biocompatibility and degradability, and it is important to make the production of the slow-release vaccine. It is used to combine with drugs to slow down the drug release in the body, thereby extending the immune effect.
• Agarose can be prepared in the form of gels or microspheres and can be used to control the rate and duration of drug release. Principle of the multi-phase targeting system.
• Agarose gel can be used as an ideal three-dimensional scaffold for cell and tissue engineering. It mimics the extracellular matrix environment, promotes cell growth and differentiation, and be applied to the repair of damaged tissues or organs.

Advantages

• Agarose-based drug delivery systems can be tailored to facilitate the targeted delivery of a diverse array of therapeutic agents, encompassing small molecules, proteins, peptides, and nucleic acids, catering to an extensive range of research requirements.
• Agarose is extremely biocompatible and it does not cause an immune response in the body, making it safe to use as a drug carrier.
• Agarose-based drug delivery systems can be prepared in different forms, such as gel, bead, or film, offering a remarkably versatile range of delivery routes.

With an unwavering commitment to excellence, CD BioGlyco has consistently provided cutting-edge agarose-based drug delivery solutions that cater to the unique needs of our clients. Our team of dedicated scientists and researchers work tirelessly to optimize every aspect of our drug delivery service. If you need the agarose-based drug delivery service, please feel free to contact us for more details.

• β-Cyclodextrin (CD)-based Drug Delivery Service
• Nanometabolic Precursors (Nano-MP)-based Drug Delivery Service
• Gel Stent-based Drug Delivery Service
• Polymer-based Drug Delivery Service
• Silica-based Nanoparticle Drug Delivery Service
• Chitosan-based Nanoparticle Drug Delivery Service
• Bioreactor-based Drug Delivery Service
• SPAAC-based Drug Delivery Service
• CuAAC-based Drug Delivery Service
• Diels-Alder Reaction-based Drug Delivery Service
• Staudinger Reaction-based Drug Delivery Service
• Mesenchymal Stem Cell (MSC)-based Drug Delivery Service