Cat. No.: X24-03-YW0209
Bromoacetamidoacetamido PEG reagent, Bromoacetamido-PEG8-acid, Purity 98%
Synonym: 1698019-89-4; Bromoacetamido-PEG8-acid; 3-[2-[2-[2-[2-[2-[2-[2-[2-[(2-Bromoacetyl)amino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid; Bromoacetamide-PEG8-acid; Bromoacetamido-PEG8- acid
- CAS Number: 1698019-89-4
- PubChem CID: 77078274
Size
100 mg; 250 mg; 500 mg
Properties
Description
Bromoacetamido-PEG8-acid is a PEG linker featuring a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer enhances solubility in aqueous environments. With the bromide (Br) serving as an efficient leaving group for nucleophilic substitution reactions, the terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g., EDC or HATU) to yield stable amide bonds.
Molecular Formula
C21H40BrNO11
Functional Group 1
Bromoacetamidoacetamido
Identity
Confirmed by NMR.
Applications
Bromoacetamido-PEG8-acid finds widespread application in bioconjugation and chemical modification processes. Its bromide moiety facilitates efficient coupling reactions, while the terminal carboxylic acid enables selective conjugation with primary amine groups of biomolecules. This reagent is commonly employed in the synthesis of bioconjugates, drug delivery systems, and biomaterials due to its water solubility and versatility in aqueous environments.
For Research Use Only. Not For
Clinical Use.