Bromoacetamidoacetamido PEG reagent, Bromoacetamido-PEG8-acid, Purity 98%

Synonym: 1698019-89-4; Bromoacetamido-PEG8-acid; 3-[2-[2-[2-[2-[2-[2-[2-[2-[(2-Bromoacetyl)amino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid; Bromoacetamide-PEG8-acid; Bromoacetamido-PEG8- acid

CAS Number: 1698019-89-4
PubChem CID: 77078274

Size

100 mg; 250 mg; 500 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Bromoacetamido-PEG8-acid is a PEG linker featuring a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer enhances solubility in aqueous environments. With the bromide (Br) serving as an efficient leaving group for nucleophilic substitution reactions, the terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g., EDC or HATU) to yield stable amide bonds.

Molecular Weight

562.5

Molecular Formula

C₂₁H₄₀BrNO₁₁

Functional Group 1

Bromoacetamidoacetamido

Functional Group 2

None

Functional Group 3

None

Reactive Group 1

Amine

Form

Liquid

Purity

98%

Solubility

Water, DCM

Identity

Confirmed by NMR.

Applications

Bromoacetamido-PEG8-acid finds widespread application in bioconjugation and chemical modification processes. Its bromide moiety facilitates efficient coupling reactions, while the terminal carboxylic acid enables selective conjugation with primary amine groups of biomolecules. This reagent is commonly employed in the synthesis of bioconjugates, drug delivery systems, and biomaterials due to its water solubility and versatility in aqueous environments.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.