3-(Acetylthio)propionic acid N-succinimidyl ester

Synonym: 84271-78-3; N-Succinimidyl-S-acetylthiopropionate; 2,5-DIOXOPYRROLIDIN-1-YL 3-(ACETYLTHIO)PROPANOATE; 3-(Acetylthio)propionic acid N-succinimidyl ester; (2,5-dioxopyrrolidin-1-yl) 3-acetylsulfanylpropanoate

CAS Number: 84271-78-3
PubChem CID: 4110341

Size

100 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

3-(Acetylthio)propionic acid N-succinimidyl ester combines an acetylthio group and a succinimidyl ester. It is frequently used in bioconjugation reactions to attach thiol-containing molecules to other biomolecules or surfaces. The succinimidyl ester provides a reactive site for coupling reactions.

Molecular Weight

245.3

Molecular Formula

C₉H₁₁NO₅S

Functional Group 1

Acid

Functional Group 2

NHS

Functional Group 3

Thioether

Reactive Group 1

Amine

Form

Solid

Identity

Confirmed by NMR.

Applications

This compound serves as a reactive acylating agent for thiol groups in peptides and proteins. It is valuable in the synthesis of modified biomolecules, enabling the attachment of acetylthio groups to enhance biological properties or stability.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.