Description
8-Arm PEG-acid is a reagent grade 8-arm branched PEG linker with four carboxylic acid groups. The terminal carboxylic acid reacts with primary amine groups in the presence of activators (EDC, HATU, etc) to form a stable amide bond.
Applications
8-Arm PEG-acid is functionalized with various biomolecules to create drug conjugates. Its high molecular weight and multiple functional groups enhance the solubility and circulation time of drugs, making it ideal for controlled release applications and improving the pharmacokinetics of therapeutics, particularly in targeted drug delivery systems.