Acid PEG reagent, Benzyl-PEG2-CH₂CO₂-t-Bu, Purity 98%

Synonym: 1309451-06-6; Benzyl-PEG2-CH₂CO₂tBu; BnO-PEG1-CH₂CO2tBu; Tert-butyl 2-(2-(benzyloxy)ethoxy)acetate; Tert-butyl 2-[2-(benzyloxy)ethoxy]acetate

CAS Number: 1309451-06-6
PubChem CID: 77078214

Size

500 mg; 1 g; 2 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Benzyl-PEG2-CH₂CO₂tBu comprises a PEG linker with a benzyl group and a t-butyl protected carbonyl. Both groups are acid-sensitive, enabling removal under acidic conditions. The carboxylic acid reacts with primary amines using activators like EDC and DCC to form stable amide bonds. The hydrophilic PEG linkers enhance water solubility in aqueous media.

Molecular Weight

266.3

Molecular Formula

C₁₅H₂₂O₄

Functional Group 1

Acid

Functional Group 2

None

Functional Group 3

None

Form

Liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

Benzyl-PEG2-CH₂CO₂tBu can be used as a versatile tool in chemical synthesis and bioconjugation. Its acid-labile benzyl and t-butyl groups afford precise control over linker activation and deprotection, facilitating the construction of various molecular architectures and functionalized surfaces.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.

Acid PEG reagent, Benzyl-PEG2-CH2CO2-t-Bu, Purity 98%

Acid PEG reagent, Benzyl-PEG2-CH₂CO₂-t-Bu, Purity 98%