Cat. No.: X24-03-YW0090
Acid PEG reagent, Benzyl-PEG2-CH2CO2-t-Bu, Purity 98%
Synonym: 1309451-06-6; Benzyl-PEG2-CH2CO2tBu; BnO-PEG1-CH2CO2tBu; Tert-butyl 2-(2-(benzyloxy)ethoxy)acetate; Tert-butyl 2-[2-(benzyloxy)ethoxy]acetate
- CAS Number: 1309451-06-6
- PubChem CID: 77078214
Properties
Description
Benzyl-PEG2-CH2CO2tBu comprises a PEG linker with a benzyl group and a t-butyl protected carbonyl. Both groups are acid-sensitive, enabling removal under acidic conditions. The carboxylic acid reacts with primary amines using activators like EDC and DCC to form stable amide bonds. The hydrophilic PEG linkers enhance water solubility in aqueous media.
Molecular Formula
C15H22O4
Identity
Confirmed by NMR.
Applications
Benzyl-PEG2-CH2CO2tBu can be used as a versatile tool in chemical synthesis and bioconjugation. Its acid-labile benzyl and t-butyl groups afford precise control over linker activation and deprotection, facilitating the construction of various molecular architectures and functionalized surfaces.
For Research Use Only. Not For
Clinical Use.