Acid/DBCO PEG reagent, DBCO-NHCO-PEG4-acid, Purity 98%

Synonym: 2110448-99-0; DBCO-NH-PEG4-CH₂CH₂COOH; SCHEMBL21694881; DTXSID301113186; AKOS040757298

CAS Number: 2110448-99-0
PubChem CID: 126480601

Size

25 mg; 100 mg; 500 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

DBCO-NHCO-PEG4-acid is a reagent grade analog of DBCO-Acid featuring a hydrophilic PEG spacer arm, which enhances water solubility. This non-activated building block is designed for derivatizing amine-containing molecules through a stable amide bond.

Molecular Weight

552.6

Molecular Formula

C₃₀H₃₆N₂O₈

Functional Group 1

Acid

Functional Group 2

DBCO

Functional Group 3

None

Reactive Group 1

Azide

Form

Liquid

Purity

98%

Solubility

DMSO, DMF, DCM

Identity

Confirmed by NMR.

Applications

DBCO-NHCO-PEG4-acid is utilized in bioconjugation and molecular biology research, enabling efficient copper-free Click Chemistry reactions. Its enhanced solubility in aqueous media and ability to form stable amide bonds with amine-containing molecules make it ideal for modifying biomolecules and studying protein interactions.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.