Description
DBCO-PEG12-acid is a reagent grade analog of DBCO-Acid featuring a hydrophilic PEG linker and a DBCO group, commonly used for Click Chemistry reactions. The hydrophilic PEG chain increases the water solubility of compounds in aqueous media.
Applications
DBCO-PEG12-acid is used in bioconjugation and molecular biology research, facilitating efficient Click Chemistry reactions. Its terminal carboxylic acid reacts with primary amine groups in the presence of activators like EDC or HATU to form stable amide bonds, making it ideal for modifying biomolecules and studying protein interactions.