Description
DBCO-PEG5-acid is a reagent grade analog of DBCO-Acid featuring a PEG linker and a highly reactive DBCO group, ideal for copper-free Click Chemistry reactions. The hydrophilic PEG chain enhances the water solubility of compounds in aqueous media.
Applications
DBCO-PEG5-acid is used in bioconjugation and molecular biology research, enabling efficient copper-free Click Chemistry reactions. Its terminal carboxylic acid reacts with primary amine groups in the presence of activators like EDC or HATU to form stable amide bonds, making it ideal for modifying biomolecules and studying protein interactions.