Cat. No.: X24-10-WXX306
Acid/DBCO PEG reagent, N-DBCO-N-bis(PEG2-amide-PEG4-acid), Purity 95%
Synonym: Acid/DBCO PEG reagent; N-DBCO-N-bis(PEG2-amide-PEG4-acid)
Properties
Description
N-DBCO-N-bis(PEG2-amide-PEG4-acid) is a reagent grade precursor of antibody-drug conjugate that contains a DBCO group and two protease-sensitive Val-Cit dipeptides with carboxylic acid groups, designed for copper-free click chemistry reactions. The acid group derivatizes amine-containing molecules in the presence of activators (EDC, HATU, etc).
Molecular Formula
C55H82N4O20
Identity
Confirmed by NMR.
Applications
N-DBCO-N-bis(PEG2-amide-PEG4-acid) is designed for bioorthogonal reactions and typically forms stable conjugates that are used to label and target cells with synthetic constructs.
For Research Use Only. Not For
Clinical Use.