Description
Sulfo DBCO-PEG3-acid is a reagent grade analog of DBCO-Acid, featuring a PEG linker and a DBCO group for copper-free Click Chemistry reactions due to its strain-promoted high energy. The hydrophilic PEG chain and sulfo group enhance water solubility, and the terminal carboxylic acid can react with primary amine groups in the presence of activators to form a stable amide bond.
Applications
Sulfo DBCO-PEG3-acid is used in bioconjugation and molecular biology research, enabling efficient copper-free Click Chemistry reactions. Its hydrophilic PEG chain and sulfo group improve solubility, while the terminal carboxylic acid allows for stable amide bond formation with primary amines, ideal for modifying biomolecules and studying protein interactions.