Cat. No.: X24-03-YW0629
Acid/Iodoacetamide PEG reagent, Iodoacetamido-PEG3-acid, Purity 98%
Synonym: Iodoacetamido-PEG3-acid
Size
50 mg; 100 mg; 250 mg
Properties
Description
Iodoacetamido-PEG3-acid is a water-soluble PEG linker featuring an iodoacetamido group and a terminal carboxylic acid. The iodoacetamido moiety acts as a potent alkylating agent for covalent thiol binding, while the terminal carboxylic acid allows for conjugation with primary amines via amide bond formation.
Molecular Formula
C11H20INO6
Functional Group 2
Iodoacetamide
Solubility
DMSO, DCM, DMF
Identity
Confirmed by NMR.
Applications
Iodoacetamido-PEG3-acid is widely used in protein labeling, bioconjugation, and drug delivery. It enables specific modification of cysteine residues, preventing disulfide bond formation, while its carboxylic acid facilitates efficient coupling with amine-containing biomolecules, making it ideal for creating stable and targeted conjugates in biomedical research.
For Research Use Only. Not For
Clinical Use.