Acid/Iodoacetamide PEG reagent, Iodoacetamido-PEG3-acid, Purity 98%

Synonym: Iodoacetamido-PEG3-acid

PubChem CID: 167312674

Size

50 mg; 100 mg; 250 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Iodoacetamido-PEG3-acid is a water-soluble PEG linker featuring an iodoacetamido group and a terminal carboxylic acid. The iodoacetamido moiety acts as a potent alkylating agent for covalent thiol binding, while the terminal carboxylic acid allows for conjugation with primary amines via amide bond formation.

Molecular Weight

389.2

Molecular Formula

C₁₁H₂₀INO₆

Functional Group 1

Acid

Functional Group 2

Iodoacetamide

Reactive Group 1

Amine

Reactive Group 2

Thiol

Form

Solid

Purity

98%

Solubility

DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Iodoacetamido-PEG3-acid is widely used in protein labeling, bioconjugation, and drug delivery. It enables specific modification of cysteine residues, preventing disulfide bond formation, while its carboxylic acid facilitates efficient coupling with amine-containing biomolecules, making it ideal for creating stable and targeted conjugates in biomedical research.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.