Description
Iodoacetamido-PEG6-acid is a hydrophilic PEG linker featuring a reactive iodoacetamido group and a terminal carboxylic acid. The PEG6 spacer enhances solubility in aqueous media. The iodoacetamido moiety selectively reacts with thiol groups, while the carboxylic acid can form stable amide bonds with primary amines.
Applications
Iodoacetamido-PEG6-acid is utilized in protein modification, bioconjugation, and drug delivery. It facilitates cysteine thiol labeling, preventing disulfide bond formation, and enables efficient coupling with amine-containing biomolecules for creating targeted and stable conjugates in biomedical research.