Acid/Maleimide PEG reagent, 3-Maleimidopropionic acid, Purity 98%

Synonym: 7423-55-4; 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoic acid; 3-(2,5-Dioxopyrrol-1-yl)propanoic acid; N-Maleoyl-beta-alanine

MDL: MFCD00043030
CAS Number: 7423-55-4
PubChem CID: 573621

Size

1 g; 5 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

3-Maleimidopropionic acid is a bifunctional molecule featuring a maleimide group and a terminal carboxylic acid. The maleimide group enables selective thiol-specific reactions to form stable covalent bonds, while the carboxylic acid reacts with primary amines in the presence of activators such as EDC or HATU to create amide linkages.

Molecular Weight

169.1

Molecular Formula

C₇H₇NO₄

Functional Group 1

Acid

Functional Group 2

Maleimide

Reactive Group 1

Amine

Reactive Group 2

Thiol

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

3-Maleimidopropionic acid is used in research for bioconjugation, protein modification, and synthesizing multifunctional biomolecules. Its dual reactivity facilitates the creation of thiol-reactive linkers and amide-linked conjugates, making it ideal for surface functionalization, crosslinking, and molecular interaction studies in experimental settings.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.