Cat. No.: X24-03-YW0758
Acid/Maleimide PEG reagent, 3-Maleimidopropionic acid, Purity 98%
Synonym: 7423-55-4; 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoic acid; 3-(2,5-Dioxopyrrol-1-yl)propanoic acid; N-Maleoyl-beta-alanine
- MDL: MFCD00043030
- CAS Number: 7423-55-4
- PubChem CID: 573621
Properties
Description
3-Maleimidopropionic acid is a bifunctional molecule featuring a maleimide group and a terminal carboxylic acid. The maleimide group enables selective thiol-specific reactions to form stable covalent bonds, while the carboxylic acid reacts with primary amines in the presence of activators such as EDC or HATU to create amide linkages.
Molecular Formula
C7H7NO4
Functional Group 2
Maleimide
Identity
Confirmed by NMR.
Applications
3-Maleimidopropionic acid is used in research for bioconjugation, protein modification, and synthesizing multifunctional biomolecules. Its dual reactivity facilitates the creation of thiol-reactive linkers and amide-linked conjugates, making it ideal for surface functionalization, crosslinking, and molecular interaction studies in experimental settings.
For Research Use Only. Not For
Clinical Use.