Acid/Maleimide PEG reagent, Mal-amido-PEG8-acid, Purity 97%

Synonym: 1334177-86-4; Mal-amido-PEG8-C2-acid; Mal-amido-PEG8-propionic Acid

MDL: MFCD13184956
CAS Number: 1334177-86-4
PubChem CID: 51340955

Size

100 mg; 1 g; 5 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Mal-amido-PEG8-acid is a PEG linker that contains a maleimide group and a terminal carboxylic acid. The maleimide group is reactive with thiol groups, forming stable covalent bonds, while the terminal carboxylic acid is reactive with primary amines in the presence of activators like EDC or HATU to form stable amide bonds. The hydrophilic PEG spacer enhances the compound’s solubility in aqueous media, making it suitable for various biological applications.

Molecular Weight

592.6

Molecular Formula

C₂₆H₄₄N₂O₁₃

Functional Group 1

Acid

Functional Group 2

Maleimide

Reactive Group 1

Amine

Reactive Group 2

Thiol

Form

Solid (low melting point)

Purity

97%

Identity

Confirmed by NMR.

Applications

Mal-amido-PEG8-acid is used in bioconjugation for attaching biomolecules to thiol groups or primary amines. It’s ideal for protein modification, drug conjugation, and surface functionalization in research and development of diagnostic and therapeutic applications.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.