Acid/Maleimide PEG reagent, Mal-PEG6-acid, Purity 98%

Synonym: 518044-42-3; Maleimide-PEG6-CH₂CH₂COOH; MFCD22056307; 1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oic acid

MDL: MFCD22056307
CAS Number: 518044-42-3
PubChem CID: 60146200

Size

100 mg; 250 mg; 500 mg; 1 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Mal-PEG6-acid is a PEG linker featuring a maleimide group and a terminal carboxylic acid. The maleimide group enables selective thiol-specific reactions to form stable covalent bonds, while the carboxylic acid reacts with primary amines in the presence of activators such as EDC or HATU to form amide linkages. The PEG6 spacer enhances solubility and hydrophilicity in aqueous media.

Molecular Weight

433.5

Molecular Formula

C₁₉H₃₁NO₁₀

Functional Group 1

Acid

Functional Group 2

Maleimide

Reactive Group 1

Amine

Reactive Group 2

Thiol

Form

Liquid

Purity

98%

Solubility

Water, DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Mal-PEG6-acid is widely used in research for bioconjugation, protein labeling, and the development of multifunctional biomolecules. Its dual-functional groups allow for thiol-specific modifications and covalent coupling with amine-containing compounds, making it suitable for synthesizing hydrophilic linkers, studying molecular interactions, and creating functionalized surfaces in experimental applications.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.