Description
Methylamino-PEG1-acid HCl salt is a PEG linker featuring a terminal carboxylic acid and a methylamine group, provided as a hydrochloride salt for stability. The carboxylic acid group allows coupling with primary amines in the presence of activators such as EDC or HATU to form stable amide bonds. The methylamine group reacts with carboxylic acids and carbonyls, and the PEG1 spacer enhances water solubility.
Applications
Methylamino-PEG1-acid HCl salt is used in research for developing multifunctional linkers, bioconjugates, and exploring covalent coupling reactions. Its carboxylic acid and methylamine groups enable dual reactivity, making it suitable for synthesizing hydrophilic compounds, surface modifications, and studying amide bond formation in experimental settings.