Description
Methylamino-PEG4-acid HCl salt is a PEG linker featuring a terminal carboxylic acid and a methylamine group, stabilized as a hydrochloride salt. The carboxylic acid group is reactive with primary amines in the presence of activators like EDC or HATU to form stable amide bonds, while the methylamine group reacts with carboxylic acids and carbonyls. The PEG4 spacer enhances water solubility and hydrophilicity.
Applications
Methylamino-PEG4-acid HCl salt is used in research for synthesizing functionalized molecules, bioconjugates, and hydrophilic linkers. Its dual-reactive groups support versatile chemical modifications, making it suitable for surface engineering, exploring molecular interactions, and designing amide-linked biomaterials for experimental studies.