Acid/Propargyl PEG reagent, N-(Acid-PEG2)-N-bis(PEG2-propargyl), Purity 98%

Synonym: N-(Acid-PEG2)-N-bis(PEG2-propargyl); 2100306-49-6; N-(PEG2-C2-acid)-N-bis(PEG2-propargyl); 10-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethyl)-4,7,13,16-tetraoxa-10-azanonadec-18-ynoic acid; 10-{2-[2-(prop-2-yn-1-yloxy)ethoxy]ethyl}-4,7,13,16-tetraoxa-10-azanonadec-18-ynoic acid

CAS Number: 2100306-49-6
PubChem CID: 126480436

Size

100 mg; 250 mg; 500 mg; 1 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

N-(Acid-PEG2)-N-bis(PEG2-propargyl) is designed for copper-catalyzed azide-alkyne click chemistry reactions with azide-bearing biomolecules or compounds. The terminal carboxylic acid reacts with primary amino groups in the presence of activators (EDC, HATU, etc) to form a stable amide bond.

Molecular Weight

429.5

Molecular Formula

C₂₁H₃₅NO₈

Functional Group 1

Acid

Functional Group 2

Propargyl

Functional Group 3

None

Reactive Group 1

Amine

Reactive Group 2

Azide

Form

Liquid

Purity

98%

Solubility

Water, DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

N-(Acid-PEG2)-N-bis(PEG2-propargyl) is used in molecular biology and bioconjugation research, promoting efficient copper-catalyzed click chemistry reactions with azide-bearing compounds to yield a stable triazole linkage, makes it a valuable tool in drug delivery, biomolecular interaction studt, and others.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.