Description
Propargyl-PEG4-S-PEG4-acid is a reagent grade PEG linker with a propargyl group and a terminal carboxylic acid, designed for copper-catalyzed azide-alkyne click chemistry reactions. The terminal carboxylic acid reacts with primary amine groups in the presence of activators (EDC, HATU, etc) forming a stable amide bond. The PEG spacer increases water solubility.
Applications
Propargyl-PEG4-S-PEG4-acid is used in molecular biology and bioconjugation research, promoting efficient copper-catalyzed click chemistry reactions with azide-bearing compounds or biomolecules, making it particularly suited for bioconjugation, drug delivery, and other applications.