Acid/S-S disulfide bond PEG reagent, Acid-PEG2-SS-PEG2-acid, Purity 98%

Synonym: 1807539-10-1; Acid-PEG2-SS-PEG2-Acid; 4,7,14,17-TETRAOXA-10,11-DITHIAICOSANEDIOIC ACID; 3-[2-[2-[2-[2-(2-Carboxyethoxy)ethoxy]ethyldisulfanyl]ethoxy]ethoxy]propanoic acid; DTXSID501234279

CAS Number: 1807539-10-1
PubChem CID: 91809454

Size

100 mg; 250 mg; 500 mg

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Acid-PEG2-SS-PEG2-acid is a homobifunctional, cleavable PEG linker with carboxylic acid groups at both termini. Carboxylic acids react with primary amines in the presence of activators like EDC and HATU to form stable amide bonds. The disulfide bonds can be cleaved by DTT reagent.

Molecular Weight

386.5

Molecular Formula

C₁₄H₂₆O₈S₂

Functional Group 1

Acid

Functional Group 2

S-S disulfide bond

Functional Group 3

None

Reactive Group 1

Amine

Form

Waxy solid

Purity

98%

Solubility

Water, DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

Acid-PEG2-SS-PEG2-acid is used in bioconjugation and molecular biology research, facilitating efficient modification of primary amines and enabling cleavable linkages in protein interactions.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.