Description
Tos-PEG2-acid is a reagent grade PEG linker with a tosyl group and a terminal carboxylic acid. The PEG spacer increases water solubility. The tosyl group is used for nucleophilic substitution reactions. The terminal carboxylic acid reacts with primary amine groups in the presence of activators (EDC, HATU, etc).
Applications
Tos-PEG2-acid acts as a derivative and finds applications in forming stable conjugates and their interaction with biomolecules, making them suitable for targeted therapies. The function group facilitates reactions that can conjugate these compounds into biomolecules, such as proteins or nucleic acids.