Description
Tos-PEG4-acid is a reagent grade PEG linker with a tosyl group and a terminal carboxylic acid. The PEG spacer increases water solubility. The tosyl group is used for nucleophilic substitution reactions. The terminal carboxylic acid reacts with primary amine groups in the presence of activators (EDC, HATU, etc).
Applications
Tos-PEG4-acid acts as a derivative and finds applications in forming stable conjugates. The function group facilitates reactions that conjugate these compounds to biomolecules, such as proteins or nucleic acids.