Description
Tos-PEG4-CH2CO2H is a reagent grade PEG linker with a terminal carboxylic acid and a tosyl group. The PEG spacer increases water solubility. The tosyl group is used for nucleophilic substitution reactions. The terminal carboxylic acid is reacted with primary amine groups in the presence of activators (EDC, HATU, etc).
Applications
Tos-PEG4-CH2CO2H serves a vital role in bioconjugation, drug delivery, and the development of biomaterials due to its ability to enhance the solubility, stability, and functionalization of bioactive molecules.