Description
Tos-PEG6-acid is a reagent grade PEG linker with a terminal carboxylic acid and a tosyl group. The PEG spacer increases water solubility. The tosyl group is used for nucleophilic substitution reactions. The terminal carboxylic acid reacts with primary amine groups in the presence of activators (EDC, HATU, etc).
Applications
Tos-PEG6-acid is primarily used in bioconjugation, drug delivery, and materials science to enhance the solubility, bioavailability, and stability of biologically active molecules by utilizing the unique properties of PEG.