Description
Biotin-PEG4-alcohol is a biotinylation reagent featuring a primary hydroxyl (OH) group that offers versatility for further derivatization. The polyethylene glycol (PEG) spacer enhances the solubility of labeled molecules, surpassing the solubility achieved by reagents with hydrocarbon spacers.
Applications
Biotin-PEG4-alcohol finds utility in various biotinylation applications, particularly in the conjugation of biotin to proteins, peptides, oligonucleotides, and other biomolecules. The hydroxyl group can be readily functionalized with reactive groups or crosslinkers, allowing for precise control over the conjugation chemistry. The resulting biotinylated compounds are valuable tools for various biochemical and biological assays, including affinity purification, immunoprecipitation, and fluorescence-based detection methods.