Description
FAM-amido hexamethylene carbamate-PAB-Cit-Val-alkyne is a reagent grade cleavable ADC linker with fluorescein, designed to undergo enzymatic transamination. The alkyne group can react with azides via copper-catalyzed Click Chemistry reactions.
Applications
FAM-amido hexamethylene carbamate-PAB-Cit-Val-alkyne is used in bioconjugation and molecular biology research, facilitating targeted drug delivery by releasing the ADC payload specifically in lysosomes due to Cathepsin B cleavage.