Description
Amine-Tri(3-methoxypropanamide-PEG23-azide) methane, HCl salt is a multifunctional PEG linker designed for bioconjugation applications. It features a central methane core with three branches, each terminating with a 3-methoxypropanamide-PEG23 chain and an azide group. The terminal amine group provides versatility for conjugation with various functional groups, including carboxylic acids, activated NHS esters, and carbonyls such as ketones and aldehydes. The presence of azide groups enables efficient PEGylation via- Click Chemistry.
Applications
Amine-Tri(3-methoxypropanamide-PEG23-azide) methane, HCl salt finds widespread utility in bioconjugation and drug delivery applications. Its multifunctional nature allows for the conjugation of diverse molecules to biomolecules or surfaces. The terminal amine group serves as a reactive handle for conjugation with various functional groups, expanding its versatility in chemical modification. Moreover, the azide groups enable efficient and selective PEGylation via- Click Chemistry reactions, providing a robust strategy for the synthesis of bioconjugates with enhanced solubility, stability, and biocompatibility.