Amine PEG reagent, Amino-PEG12-t-butyl ester, Purity 98%

Synonym: 872340-65-3; Amino-PEG12-t-butyl ester; Amino-PEG12-Boc; H₂N-PEG12-CH₂CH₂COOtBu

CAS Number: 872340-65-3
PubChem CID: 53433574

Size

100 mg; 500 mg; 1 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Amino-PEG12-t-butyl ester is a water-soluble PEG linker featuring an amino group (NH₂) and a t-butyl protected carboxyl group (Boc), facilitating aqueous applications.

Molecular Weight

673.8

Molecular Formula

C₃₁H₆₃NO₁₄

Functional Group 1

Amine

Functional Group 2

None

Functional Group 3

None

Reactive Group 1

Carboxylic acid

Reactive Group 2

Carbonyls

Reactive Group 3

NHS

Form

Liquid

Purity

98%

Solubility

Water, DMSO, DMF, DCM

Identity

Confirmed by NMR.

Applications

Amino-PEG12-t-butyl ester can be used as a versatile tool for bioconjugation reactions in aqueous environments. Its amino group reacts with various functional groups including carboxylic acids, activated NHS esters, and carbonyls, enabling the conjugation of biomolecules for drug delivery, diagnostics, and biotechnology applications. Additionally, the t-butyl protected carboxyl group can be selectively deprotected under acidic conditions, enhancing its utility in controlled-release systems and surface functionalization.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.