Description
Amino-tri-(azide-PEG10-ethoxymethyl)-methane, HCl Salt is a branched PEGylation reagent comprising an amino group with three azide functionalities. This compound's amino group exhibits reactivity towards carboxylic acids and activated NHS esters. The azide groups present in the molecule are capable of undergoing Click Chemistry reactions with alkynes, BCN, and DBCO, resulting in the formation of stable triazole linkages.
Applications
Amino-tri-(azide-PEG10-ethoxymethyl)-methane, HCl Salt finds extensive use in bioconjugation and chemical biology applications. Its reactive amino group allows for efficient coupling with various biomolecules and functionalized substrates, enabling the introduction of PEG moieties or other chemical entities. The azide groups facilitate selective conjugation reactions with alkyne-containing molecules, facilitating the synthesis of complex bioconjugates, drug delivery systems, and biomaterials.