Amine PEG reagent, Bromoacetamido-PEG3-Boc-amine, Purity 98%

Synonym: 1421933-39-; Bromoacetamido-PEG3-Boc-amine; Bromoacetamido-PEG3-NH-Boc; Tert-butyl (1-bromo-2-oxo-6,9,12-trioxa-3-azatetradecan-14-yl)carbamate; Tert-butyl N-[2-[2-[2-[2-[(2-bromoacetyl)amino]ethoxy]ethoxy]ethoxy]ethyl]carbamate

CAS Number: 1421933-39-2
PubChem CID: 77078467

Size

250 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Bromoacetamido-PEG3-Boc-amine is a PEG linker with a Boc-protected amino group and a bromide moiety. The Boc group can be selectively removed under mild acidic conditions, exposing the free amino group for further reactions. The bromide serves as an excellent leaving group for nucleophilic substitution reactions. Additionally, the hydrophilic PEG spacer enhances the compound's solubility in aqueous solutions.

Molecular Weight

413.3

Molecular Formula

C₁₅H₂₉BrN₂O₆

Functional Group 1

Amine

Functional Group 2

None

Functional Group 3

None

Reactive Group 1

Carboxylic acid

Reactive Group 2

Carbonyls

Reactive Group 3

NHS

Form

Liquid

Purity

98%

Identity

Confirmed by NMR.

Applications

Bromoacetamido-PEG3-Boc-amine is widely utilized in bioconjugation chemistry and drug delivery systems. The exposed amino group enables the conjugation of various molecules, such as proteins, peptides, or drugs, through amidation reactions. The bromide group facilitates nucleophilic substitution reactions, allowing for further functionalization or modification of the PEG linker.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.