Cat. No.: X24-03-YW0128
Amine PEG reagent, Fmoc-Glu(biotinyl-PEG)-OH, Purity 95%
Synonym: 817169-73-6; Fmoc-Glu(biotinyl-PEG)-OH; (2S)-5-[3-[2-[2-[3-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-Hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]propoxy]ethoxy]ethoxy]propylamino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxopentanoic acid; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5,21-dioxo-25-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-10,13,16-trioxa-6,20-diazapentacosanoic acid
- CAS Number: 817169-73-6
- PubChem CID: 71310913
Size
100 mg; 250 mg; 500 mg; 1 g
Properties
Description
Fmoc-Glu(biotinyl-PEG)-OH is a biotinylation reagent featuring a terminal Fmoc group. The biotin moiety at the terminal end allows for conjugation with amine molecules in the presence of activators such as EDC or HATU. The Fmoc group serves as a protecting group and can be selectively removed under basic conditions to expose the free amine for subsequent conjugation reactions.
Molecular Formula
C40H55N5O10S
Identity
Confirmed by NMR.
Applications
Fmoc-Glu(biotinyl-PEG)-OH finds application in the site-specific biotinylation of proteins and peptides. The conjugation of the biotin moiety to amine-containing molecules enables downstream applications such as affinity purification, protein detection, and protein labeling. The selective deprotection of the Fmoc group allows for precise control over the modification process, facilitating the generation of biotinylated molecules with high purity and yield.
For Research Use Only. Not For
Clinical Use.
