Description
t-Boc-N-amido-PEG18-amine is a versatile PEG linker with a Boc-protected amine and a free amine group. The hydrophilic PEG spacer enhances its solubility in aqueous solutions. The Boc group can be selectively removed under mild acidic conditions, exposing the free amine for subsequent conjugation reactions.
Applications
t-Boc-N-amido-PEG18-amine can be used in bioconjugation, drug delivery, and surface modification applications. The reactive amine groups facilitate the conjugation of the linker to various biomolecules, such as proteins, peptides, and nucleic acids, through amide bond formation. The selective deprotection of the Boc group enables precise control over the functionalization process, making it suitable for the synthesis of advanced bioconjugates and targeted drug delivery systems.