Amine PEG reagent, t-Boc-N-amido-PEG5-amine, Purity 98%

Synonym: 189209-27-6; t-Boc-N-amido-PEG5-amine; Tert-butyl (17-amino-3,6,9,12,15-pentaoxaheptadecyl)carbamate; NH₂-PEG5-C2-NH-Boc; NHBoc-PEG5-amine

CAS Number: 189209-27-6
PubChem CID: 60146195

Size

250 mg; 500 mg; 1 g; 5 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

t-Boc-N-amido-PEG5-amine is a PEG linker with a Boc-protected amino group and five PEG units. The hydrophilic PEG spacer enhances solubility in aqueous environments. The amino group is reactive with various functional groups like carboxylic acids and activated NHS esters. The Boc protection can be selectively removed under mild acidic conditions, freeing the amine for conjugation reactions.

Molecular Weight

380.5

Molecular Formula

C₁₇H₃₆N₂O₇

Functional Group 1

Amine

Functional Group 2

None

Functional Group 3

None

Reactive Group 1

Carboxylic acid

Reactive Group 2

Carbonyls

Reactive Group 3

NHS

Form

Liquid

Purity

98%

Solubility

Water, DMSO, DCM, DMF

Identity

Confirmed by NMR.

Applications

t-Boc-N-amido-PEG5-amine can be used in bioconjugation, drug delivery, and surface modification. Its bifunctionality enables the conjugation of biomolecules, polymers, or drugs to surfaces or other molecules via- amide bond formation. The controlled deprotection of the Boc group ensures precise control over the reaction conditions, facilitating efficient and selective chemical modifications.

Storage

Store at -20°C

For Research Use Only. Not For Clinical Use.