Amine/Azide PEG reagent, 2-(Azido-PEG2-amido)-1,3-bis(t-butyldimethylsilanoxy)propane, Purity 96%

Synonym: 1398044-56-8; 2-(Azido-PEG2-amido)-1,3-bis(tert-butyldimethylsilanoxy)propane; 2-(Azido-peg2-amido)-1,3-bis(tertbutyldimethylsilanoxy)propane; 3-[2-(2-azidoethoxy)ethoxy]-N-[1,3-bis[[tert-butyl(dimethyl)silyl]oxy]propan-2-yl]propanamide; 2-(Azido-PEG2-amido)-1,3-bis-(tert-butyldimethylsilanoxy)propane

CAS Number: 1398044-56-8
PubChem CID: 77078516

Size

250 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

2-(Azido-PEG2-amido)-1,3-bis(t-butyldimethylsilanoxy)propane acts as a PEG linker that includes a TBDMS acid-labile alcohol protecting group. Its azide group participates in copper-catalyzed click chemistry reactions involving alkynes such as DBCO and BCN to generate triazole linkages. Moreover, the hydrophilic nature of this PEG linker improves solubility characteristics of compounds in aqueous media.

Molecular Weight

504.8

Molecular Formula

C₂₂H₄₈N₄O₅Si₂

Functional Group 1

Azide

Functional Group 2

Amine

Functional Group 3

t-Butyl

Reactive Group 1

Alkynyl

Reactive Group 2

Acid

Form

Solid

Purity

96%

Identity

Confirmed by NMR.

Applications

It can be applied in the synthesis of advanced materials or in the development of novel drug candidates.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.