Amine/Azide PEG reagent, Amino-PEG4-t-Boc-hydrazide, Purity 96%

Synonym: 1263047-17-1; Amino-PEG4-t-Boc-Hydrazide; Amino-PEG4-hydrazide-Boc; NH₂-PEG4-HZ-Boc; 2-BOC-Hydrozino 3-amino(peg4)propionamide

CAS Number: 1263047-17-1
PubChem CID: 51340924

Size

100 mg; 500 mg; 1 g

Price

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Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Amino-PEG4-t-Boc-hydrazide acts as a PEG linker featuring both an amino group and a Boc-protected hydrazide moiety. Its hydrophilic PEG spacer increases solubility when placed into aqueous media. The amine group exhibits reactivity towards carboxylic acids, activated NHS esters, and carbonyls (including ketones and aldehydes). Similar to other products, the Boc protecting group can be removed under mild acidic conditions to form a reactive hydrazide that may couple with various carbonyl compounds afterward.

Molecular Weight

379.5

Molecular Formula

C₁₆H₃₃N₃O₇

Functional Group 1

Boc

Functional Group 2

Amine

Functional Group 3

Azide

Reactive Group 1

Acid

Reactive Group 2

Alkynyl

Form

Solid

Purity

96%

Identity

Confirmed by NMR.

Applications

Amino-PEG4-t-Boc-hydrazide is often utilized in the synthesis of modified peptides and small molecules. The amino group can be used for further chemical modifications, while the Boc group provides protection. The PEG4 moiety improves solubility. It can be applied in the development of drug candidates or as a linker in the construction of biomolecular conjugates.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.