Amine/Azide PEG reagent, Amino-PEG8-t-Boc-hydrazide, Purity 98%

Synonym: 1334169-96-8; Amino-PEG8-t-Boc-Hydrazide; Amino-PEG8-hydrazide-Boc; NH₂-PEG8-HZ-Boc; tert-butyl 30-amino-4-oxo-7,10,13,16,19,22,25,28-octaoxa-2,3-diazatriacontan-1-oate

CAS Number: 1334169-96-8
PubChem CID: 75535022

Size

100 mg; 500 mg; 1 g

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Amino-PEG8-t-Boc-hydrazide serves as a crosslinker featuring an amino group along with a Boc-protected hydrazide. Its hydrophilic PEG spacer improves solubility in water-based environments. The amine group reacts with carboxylic acids, activated NHS esters, and carbonyls (such as ketones and aldehydes). The Boc protecting group can be removed under mild acidic conditions to yield a reactive hydrazide that can subsequently couple with various carbonyl compounds.

Molecular Weight

555.7

Molecular Formula

C₂₄H₄₉N₃O₁₁

Functional Group 1

Boc

Functional Group 2

Amine

Functional Group 3

Azide

Reactive Group 1

Acid

Reactive Group 2

Alkynyl

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

In the field of drug discovery, amino-PEG8-t-Boc-hydrazide can be employed to modify potential drug molecules to improve their solubility and pharmacokinetic properties. It can also be utilized in the conjugation of biomolecules for targeted drug delivery or as a building block for the synthesis of complex biomolecular probes.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.