Amine/Azide PEG reagent, Azido-amido-PEG8-t-butyl ester, Purity 98%

Synonym: Azido-PEG4-amido-PEG4-Boc; Azido-(amido-PEG8)-t-butyl ester

Size

100 mg; 500 mg

Price

Inquiry

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Azido-amido-PEG8-t-butyl ester is a PEG linker that incorporates an azide group along with a t-butyl ester. The hydrophilic nature of the PEG spacer enhances solubility in aqueous solutions. This azide moiety can react with alkyne compounds, BCN, and DBCO through click chemistry methods to form stable triazole linkages. Additionally, the t-butyl protected carboxylic acid can be deprotected under acidic conditions.

Molecular Weight

594.7

Molecular Formula

C₂₆H₅₀N₄O₁₁

Functional Group 1

t-Butyl ester

Functional Group 2

Amine

Functional Group 3

Azide

Reactive Group 1

Acid

Reactive Group 2

Alkynyl

Form

Solid

Purity

98%

Identity

Confirmed by NMR.

Applications

In the field of drug delivery, it can be used to modify drug molecules to increase their solubility and stability, and to control their release kinetics. It can also be used in the modification of biomolecules such as proteins or antibodies to improve their properties and functionality.

Storage

Store at -20°C.

For Research Use Only. Not For Clinical Use.